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Hiroshi Kono

Faculty
Department of Health Care and Sports
Course of Health Care and Sports
Research Institute of Industrial Technology
PositionProfessor
Mail
HomepageURL
Birthday
Last Updated :2019/11/07

Researcher Profile and Settings

Degree

  • Ph.D. in Medical Sciences

Association Memberships

  • American College of Sports Medicine
  • JAPAN SOCIETY OF PHYSICAL EDUCATION, HEALTH AND SPORT SCIENCES
  • JAPANESE ASSOCIATION OF EXERCISE EPIDEMIOLOGY

Research Activities

Research Areas

  • Health/Sports science, Sports science
  • Health/Sports science, Applied health science

Research Interests

    Physical Activity, Fall Prevention, aging, Health Education

Published Papers

  • Development of a Physical Exercise Program for Community-Dwelling Elderly, 神野 宏司, 岩本 紗由美, 坂口 正治, 齋藤 恭平, 松尾 順一, 野村 豊子, ライフデザイン学研究, ライフデザイン学研究, (11) 97 - 106
  • Development of Fear-of-Fall Risk Prevention Program Using Behavior Science, 神野 宏司, 浅井 英典, ライフデザイン学研究, ライフデザイン学研究, (9) 151 - 160
  • Effects of a 5-year exercise-centered health-promoting programme on mortality and ADL impairment in the elderly., Oida Y, Kitabatake Y, Nishijima Y, Nagamatsu T, Kohno H, Egawa K, Arao T, Age and ageing, 32, (6) 585 - 592, 11 , Refereed
  • A 6-year cohort study on relationship between functional fitness and impairment of ADL in community-dwelling older persons., Nagamatsu T, Oida Y, Kitabatake Y, Kohno H, Egawa K, Nezu N, Arao T, Journal of epidemiology / Japan Epidemiological Association, 13, (3) 142 - 148, 05 , Refereed
  • Contribution of nitric oxide, angiotensin II and superoxide dismutase to exercise-induced attenuation of blood pressure elevation in spontaneously hypertensive rats., Kohno H, Furukawa S, Naito H, Minamitani K, Ohmori D, Yamakura F, Japanese heart journal, 43, (1) 25 - 34, 01 , Refereed

Misc

  • 行動科学手法を用いた転倒不安対策プログラムによる身体機能向上効果の検討, 神野宏司, 浅井英典, 体力科学, 62,   2013 12 01
  • 参加者との共同作成運動プログラムが地域在宅高齢女性の運動実施状況に及ぼす影響, 神野宏司, 浅井英典, 日本公衆衛生学会総会抄録集, 72nd,   2013 10 15
  • 地域在住中高齢者を対象とした種目選択型健康運動講座の一過性の感情および身体機能からの評価, 神野宏司, 鈴木智子, 岩本紗由美, 金子元彦, 古川覚, 齋藤恭平, 坂口正治, 松尾順一, 体力科学, 61,   2012 12 01
  • Effects of knee strength improvement program collaborated with participants using behavior science, 神野 宏司, 浅井 英典, ライフデザイン学研究, (8) 119 - 127,   2012
  • レジスタンストレーニングと継続支援プログラムの組み合わせが在宅高齢女性の身体機能に及ぼす効果, 神野宏司, 浅井英典, 体力科学, 60,   2011 12 01
  • Effects of Combined Exercise Program to Mood Change and Physical Fitness for Community-Dwelling Middle-Aged and Aged People, 神野 宏司, 鈴木 智子, 岩本 紗由美, ライフデザイン学研究, (7) 131 - 142,   2011
  • Development of community sports leaders training program on the cooperation of university and administrative agency, 齊藤 恭平, 鈴木 哲郎, 神野 宏司, ライフデザイン学研究, (7) 387 - 390,   2011
  • The study for the differeces of the physical and mental situation, and effects of exercise training programs for frail elderly people at high risk of needing long-term care and general elderly people, 浅井 英典, 神野 宏司, 愛媛大学教育学部保健体育紀要, 7,   2010 03
  • 空間認知能力の年代別差違, 神野宏司, 浅井英典, 大迫正文, 体力科学, 58,   2009 12 01
  • 行動科学手法を用いた住民参加型運動プログラムの開発, 神野宏司, 浅井英典, 日本公衆衛生学会総会抄録集, 68th,   2009 10 15
  • 身体活動・運動疫学研究における重要論文20本, 今井(武田)富士美, 中田由夫, 岡浩一朗, 北畠義典, 原田和弘, 神野宏司, 井上茂, Res Exerc Epidemiol, 11,   2009 03 31
  • The study for the physical and mental effcts of various exerise training programs for elderly people, 浅井 英典, 神野 宏司, 愛媛大学教育学部保健体育紀要, 6,   2009 03
  • 個別性を考慮した高齢者に対するレジスタンストレーニングプログラムおよび家族向け継続支援が生活機能に及ぼす影響, 神野宏司, 浅井英典, 体力科学, 57,   2008 12 01
  • 大都市近郊介護系施設における介護予防および健康づくり活動の実施状況, 神野宏司, 柴田範子, 金子元彦, 日本公衆衛生学会総会抄録集, 67th,   2008 10 15
  • Effect of endurance exercise training on nitrative stress of the heart after the emergence of hypertension in spontaneously hypertensive rats, FURUKAWA SATOSHI, KIMURA HIROKO, MUKAIDA MASAHIRO, YAMAKURA FUMIYUKI, KONO HIROSHI, IKEDA KEIICHI, 順天堂医学, 54, (3) 308 - 317,   2008 09 30 , Objective : We investigated the effects of exercise training starting after emergence ofhypertension (15-week old) on nitrative stress and protein levels and activities of nitrative stress-related enzymes in the hearts of spontaneously hypertensive rats (SHR). Material and Methods I We examined the hearts of 25-week old (wk) SHR that performed either 10 wk of voluntary exercise training (Ex) or remained intact (Cont). We also analyzed 5 wk and 15 wk SHR in order to determine basal alterations of nitrative stress and enzymes. Starting at 15 weeks old, 25 wk Ex SHR exercised by voluntary running in a wheel-cage for 10 weeks. At the end of the breeding or training period, rats were anesthetized and hearts were collected. We measured the level of nitrotyrosine by the time-resolved fluoroimmunoassay method, the amount of manganese-containing (Mn-) and copper/zinc-containing (Cu, Zn-) superoxide dismutase (SOD), and endothelial nitric oxide synthase (eNOS) in the heartby the western blotting method. Furthermore Mn- and Cu, Zn-SOD and total NOS activity were measured by the spectrometry method. Result : Systolic blood pressure was elevated at 15 wk and remained high until 25 wk Cont SHR. Exercise did not affect the blood pressure. Although there was no significant increase in 3-nitrotyrosine (3-NT) concentration in 100,000 g precipitate fractions (P2) of heart homogenate of 15wk SHR, a significant increase in 3-NT concentration was observed in that of 25 wk Cont SHR. This increase in 3-NT concentration was significantly attenuated in that of 25 wk Ex SHR. The same alterations of 3-NT levels were observed by immunohistochemical analysis using specific antibody for 3-NT. Protein levels of endothelial nitric oxide synthase (eNOS) in the membrane fractions were reduced in 15wk and 25wk Cont SHR compared with those of 5 wk SHR, but not affected by Ex. This evidence was supported by the measurements of total NOS activity in the same fractions. Protein levels of Cu, Zn-SOD were reduced to a greater degree in 25wk Ex and Cont SHR than in those of 5wk and 15wk SHR, but there was no significant effect observed by Ex. The same results were obtained upon measurement of Cu, Zn-SOD activity. However, protein of Mn-SOD increased significantly in 15 wk SHR, compared to that of 5 wk SHR. Although there was no significant difference in Mn-SOD levels between 25 wk Cont SHR and 15 wk SHR, significant increases in Mn-SOD levels and activity were observed in 25 wk Ex SHR, compared with those of 25 wk Cont SHR. This evidence accounts for the significant attenuation of 3-NT formation in the P2 fraction of 25 wk Ex SHR. Conclusion : We conclude that 10 weeks of exercise training after the emergence of hypertension could reduce nitrative stress in the organelle fractions of the heart as a result of the increase in Mn-SOD.
  • Effect of endurance exercise training on nitrative stress of the heart after the emergence of hypertension in spontaneously hypertensive rats, FURUKAWA SATOSHI, KIMURA HIROKO, MUKAIDA MASAHIRO, YAMAKURA FUMIYUKI, KOHNO HIROSHI, IKEDA KEIICHI, Juntendo Medical Journal, 54, (3) 308 - 317,   2008 , Objective: We investigated the effects of exercise training starting after emergence of hypertension (15-week-old) on nitrative stress and protein levels and activities of nitrative stress-related enzymes in the hearts of spontaneously hypertensive rats (SHR).Material and Methods: We examined the hearts of 25-week old (wk) SHR that performed either 10 wk of voluntary exercise training (Ex) or remained intact (Cont). We also analyzed 5 wk and 15 wk SHR in order to determine basal alterations of nitrative stress and enzymes. Starting at 15 weeks old, 25 wk Ex SHR exercised by voluntary running in a wheel-cage for 10 weeks. At the end of the breeding or training period, rats were anesthetized and hearts were collected. We measured the level of nitrotyrosine by the time-resolved fluoroimmunoassay method, the amount of manganese-containing (Mn-) and copper/zinc-containing (Cu, Zn-) superoxide dismutase (SOD), and endothelial nitric oxide synthase (eNOS) in the heart by the western blotting method. Furthermore Mn- and Cu, Zn-SOD and total NOS activity were measured by the spectrometry method.Result: Systolic blood pressure was elevated at 15 wk and remained high until 25 wk Cont SHR. Exercise did not affect the blood pressure. Although there was no significant increase in 3-nitrotyrosine (3-NT) concentration in 100,000g precipitate fractions (P2) of heart homogenate of 15 wk SHR, a significant in crease in 3-NT concentration was observed in that of 25 wk Cont SHR. This increase in 3-NT concentration was significantly attenuated in that of 25 wk Ex SHR. The same alterations of 3-NT levels were observed by immunohistochemical analysis using specific antibody for 3-NT. Protein levels of endothelial nitric oxide synthase (eNOS) in the membrane fractions were reduced in 15 wk and 25 wk Cont SHR compared with those of 5 wk SHR, but not affected by Ex. This evidence was supported by the measurements of total NOS activity in the same fractions. Protein levels of Cu, Zn-SOD were reduced to a greater degree in 25 wk Ex and Cont SHR than in those of 5 wk and 15 wk SHR, but there was no significant effect observed by Ex. The same results were obtained upon measurement of Cu, Zn-SOD activity. However, protein of Mn-SOD increased significantly in 15 wk SHR, compared to that of 5 wk SHR. Although there was no significant difference in Mn-SOD levels between 25 wk Cont SHR and 15 wk SHR, significant increases in Mn-SOD levels and activity were observed in 25 wk Ex SHR, compared with those of 25 wk Cont SHR. This evidence accounts for the significant attenuation of 3-NT formation in the P2 fraction of 25 wk Ex SHR.Conclusion: We conclude that 10 weeks of exercise training after the emergence of hypertension could reduce nitrative stress in the organelle fractions of the heart as a result of the increase in Mn-SOD.
  • 虚弱高齢者の生活機能改善を目的としたセルフケアプログラムの開発, 神野宏司, 古川覚, 浅井英典, 体力科学, 56,   2007 12 01
  • 個別性を考慮した運動選択型健康づくりプランが地域在宅中高齢女性の体力に及ぼす影響, 神野宏司, 金子元彦, 浅井英典, 日本公衆衛生学会総会抄録集, 66th,   2007 10 15
  • 血圧上昇期の自発運動が自然発症高血圧ラットの心筋一酸化窒素合成酵素に及ぼす影響, 神野宏司, 古川覚, 池田啓一, 内藤久士, 山倉文幸, 体力科学, 55,   2006 12 01
  • 健康教室に参加した地域在宅中高齢者の身体および日常運動実施・継続状況, 神野宏司, 金子元彦, 浅井英典, 日本公衆衛生学会総会抄録集, 65th,   2006 10 15
  • 地域在宅中高齢女性に対するバランスボールを用いた健康教室の生活機能,およびQOLに及ぼす効果, 神野宏司, 浅井英典, 古川覚, 金子元彦, 大迫正文, 鈴木哲郎, 体力科学, 54,   2005 12 01
  • バランスボールを用いた運動プログラムが地域在宅中高齢女性の生活機能に及ぼす効果, 神野宏司, 金子元彦, 浅井英典, 日本公衆衛生学会総会抄録集, 64th,   2005 08 15
  • ラット尾部懸垂に伴う膝側副靭帯の構造変化, 古川覚, 内匠屋潔, 馬場麻人, 神野宏司, 野中卓, 体力科学, 50,   2001 12 01
  • 4.Significance of NO in exercise induced suppression of resting high blood pressure, KOHNO HIROSHI, Japanese Journal of Physical Fitness and Sports Medicine, 50,   2001 10 01
  • 筋の発育方向に関する組織学的研究, 野中卓, 鈴木哲郎, 大迫正文, 中村千秋, 浅井英典, 神野宏司, 古川覚, 金子元彦, 体力科学, 49,   2000 12 01
  • 自然発症高血圧ラットにおける一酸化窒素合成酵素阻害剤静脈投与による安静時血圧応答に対する自発走トレーニングの影響, 神野宏司, 古川覚, 内藤久士, 大迫正文, 山倉文幸, 荒尾孝, 体力研究, (99) 25 - 27,   2000 11 30
  • ラット下腿筋膜の構造と機能に関する観察, 野中卓, 清水達雄, 鈴木哲郎, 大迫正文, 馬場麻人, 浅井英典, 神野宏司, 古川覚, 体力科学, 48,   1999 12 01
  • Effect of Prolonged Exercisr on Muscle Protein, Kono Hiroshi, Memoirs by the members of Senzoku-Gakuen College, 22,   1993 12 20
  • 16.A comparision on the physical characteristics of soccer, baseball, basket ball, soft ball player and long distance runner, NAKAIMA NORISHIGE, TAKAZAKURA EISUKE, NAKAGAMI AKIRA, TSUJI HIROSHI, NISHIKAWA HIROSHI, FUJII KOHJI, TIKAWA TAKASHI, IZUMI ICHIROU, KOUNO KOUJI, Japanese Journal of Physical Fitness and Sports Medicine, 42, (5) 518 - 519,   1993 10 01
  • 11. A Comparision on the physical characteristics (VO_2 max, MALP, muscle power)of soccer, baseball, basketball player and long distance runner, NAKAIMA Norishige, TAKAZAKURA Eisuke, NAKAGAMI Akira, TSUJI Hiroshi, NISHIKAWA Hiroshi, TSUBO Masahiko, FUJII Kohji, CHIKAWA Takashi, IZUMI Ichirou, KOUNO Kouji, Japanese Journal of Physical Fitness and Sports Medicine, 41,   1992 08 01
  • Physical Fitness of Maintenance Engineers under Different Working Conditions, Yabuta Toshihiko, Kono Hiroshi, Izumi Ichirou, The bulletin of Takaoka College of Law, 3,   1992 03 31 , 近年の産業の発展は24時間体制での産業活動を必要とし,多くの職場で交代で24時間操業し続けるようになっている。労働はロボットなど機械化が進み省力化が進んでいるが,それらの機器を保守点検する任務は最終的には人の仕事である。したがって機械を24時間動かし続けるためには人も24時間働かなくてはならない。このような従来とは異なる労働形態を長期間にわたって続けることが身体に及ぼす影響を知ることは重要なことと考えられる。 また,企業の健康管理は定年の延長が進み,従業員の年齢も年々高くなることから医療費に対する企業の負担,従業員の疾病による休業に対する対策など企業の運営に及ぼされる影響も考えなくてはならない問題である。本研究では今後企業の健康管理対策を考える上での基礎資料を得るために24時間3交代制勤務の従業員と通常勤務の従業員における日常生活に対するアンケートならびに最大下運動負荷テストから得た知見について報告する。
  • Nutritional Problems Competitive Cyclists, Kono Hirosi, Memoirs by the members of Senzoku-Gakuen College, 20,   1991 12 20
  • 8. Physical Fitness of Maintenance Engineers under Different Working Conditions., KONO HIROSHI, IZUMI ICHIRO, MINABE TADAO, NAKAIMA NORINARI, NAKAGAMI AKIRA, Japanese Journal of Physical Fitness and Sports Medicine, 40,   1991 08 01
  • 9. The effect of prolonged walking on urinary Amino acid, KONNO HIROSHI, IZUMI ICHIRO, MINABE TADAO, NAKAIMA NORINARI, NAKAGAMI AKIRA, Japanese Journal of Physical Fitness and Sports Medicine, 40, (2) 254 - 255,   1991 04 01
  • A Study of Uninary Creatinine Assay Method and the Problems with Assay, Kono Hirochi, Memoirs by the members of Senzoku-Gakuen College, 19,   1990 12 20
  • Change of bloood pressure during treadmill exercise test in men, MINABE TADAO, YOSHIZAKI TORU, IZUMI ICHIRO, KOHNO HIROSHI, Japanese Journal of Physical Fitness and Sports Medicine, 39,   1990 12 01
  • Physical-physiological responces during prolonged walking exercise, IZUMI ICHIRO, KOHNO HIROSHI, MINABE TADAO, NAKAIMA NORINARI, NAKAGAMI AKIRA, Japanese Journal of Physical Fitness and Sports Medicine, 39,   1990 12 01
  • Effects of a 10-week suoolementation of elemental diet on physical performance and capacity in cyclists, KOHNO Hiroshi, AOKI Junichiro, HONMA Hisako, MORITA Yasuo, TERAKADO Takao, Japanese Journal of Physical Fitness and Sports Medicine, 39,   1990 12 01
  • Significance of blood pressure measurement during exercise, NAKAYAMA AKIRA, KOHNO HIROSHI, KOBAYASHI SATORU, SAITOH TOSHIHIRO, Japanese Journal of Physical Fitness and Sports Medicine, 38,   1989 12 01
  • The Effect of High Intensity-Shot and Low Intensity-Long Duration Aerobic Exercise on Urinary 3-methylhistidine and Creatinine Excretion., Kohno Hiroshi, Aoki junichiro, Ohta Yoshiyuki, Japanese Journal of Physical Fitness and Sports Medicine, 38,   1989 12 01
  • Effects of shouting on muscular activity during fatigue, ASAI HIDENORI, KOUNO HIROSHI, Japanese Journal of Physical Fitness and Sports Medicine, 36,   1987 12 01
  • 3. Motor intensity of fundamental skills in women's volleyball, KAGATA HATSUMI, INAGAKI ATSUSHI, KOUNO HIROSHI, SUGIYAMA MASAHIRO, Japanese Journal of Physical Fitness and Sports Medicine, 35,   1986 08 01
  • 9. Motor intensity of the basic skill in tennis, MIYOSHI TAKASHI, KOUNO HIROSHI, SUGIYAMA MASAHIRO, Japanese Journal of Physical Fitness and Sports Medicine, 34,   1985 08 01

Conference Activities & Talks

  • 地域老人会における手遊び、指遊び体操が対人交流に及ぼす影響, Hiroshi Kohno, The Japanese Society of Health, Fitness and Nutrition.,   2019 03 16 , The Japanese Society of Health, Fitness and Nutrition.
  • Effects of Three-stages Training Program on Seikatsu-Tairyoku and Fear of Falling Score for Community-Dwelling Old-old Japanese, Hiroshi Kohno, Japanese Society of Physical Fitness and Sports Medicine,   2018 09 08 , Japanese Society of Physical Fitness and Sports Medicine

Research Grants & Projects

  • Functional Fitness for Elderly, Basic Research Promotion Service for Health and Medical Field